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St. John Health System
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Mitochondrial M2 Antibody, IgG

Order Name MITOCH M2
Test Number: 5574400
Revision Date 06/26/2023
Test Name Methodology LOINC Code
Mitochondrial M2 Antibody, IgG
Chemiluminescence, Immunoassay 14251-3 
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 0.5mL (0.3) Serum Clot Activator SST Refrigerated
Instructions Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL(Min: 0.3 mL) to a Standard Transport Tube.
Unacceptable Conditions: Plasma. Contaminated, hemolyzed, grossly icteric, or severely lipemic specimens.
Stability After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
GENERAL INFORMATION
Testing Schedule Mon-Fri 
Expected TAT 1-2 days 
Clinical Use Mitochondrial Antibody is present in approximately 95% of patients with primary biliary cirrhosis (PBC). Mitochondrial M2 Antibody has an even higher specificity for PBC. 
CPT Code(s) 86381
Internal Comments 10/16/17 change cpt from 83520 to 83516 - JK
7/19/18 Please make the following changes to RML Online for MITOCH M2 (5574400) - JK
1) Add statement ":Separate serum from cells ASAP or within 2 hours of collection. Submit specimen at refrigerated temp"
2) Specimen volume: change from 1mL (0.3mL) to 0.5mL (0.3mL)
3) Add "Unacceptable:Plasma. Contaminated, hemolyzed, grossly icteric, or severely lipemic specimens"
4) Update stabilities to "Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)"
5) Update Testing Schedule to "Sun-Sat" & TAT to 1-2 days after set-up
6) LOINC - 14251-3
--------------------------------------------------------
2022 cpt from
83516 to 86381 - JK
1/24/2022 moved to RML
removed
Reference Lab: ARUP
Test Code: 50065
Click Here to view information on the ARUP website.
6/26/23 Update TAT & Testing schedule - SN
Service Provided By Labcorp Oklahoma, Inc.
Lab Section Immunology - Serology