Mitochondrial M2 Antibody, IgG
Order Name
MITOCH M2
Test Number: 5574400
Revision Date 07/10/2025
Test Number: 5574400
Revision Date 07/10/2025
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
Mitochondrial M2 Antibody, IgG
|
Enzyme-Linked Immunosorbent Assay (ELISA) | 14251-3 |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 0.5mL (0.3mL) | Serum | Clot Activator (SST or Red No-Gel) | Room Temperature |
| Instructions | Specimen: 1mL (0.3mL Note: This volume does not allow for repeat testing.) Serum from Red-top tube or gel-barrier tube Stability Requirements: Room temperature 14 days, Refrigerated 14 days, Frozen 14 days (Freeze/thaw cycles Stable x3) Cause for Rejection: Hemolysis; lipemia; gross bacterial contamination; heat-treated specimen; specimen with preservative added. |
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| GENERAL INFORMATION | |
|---|---|
| Expected TAT | 2-4 days |
| Clinical Use | Antimitochondrial antibodies (AMA) have been reported in 90% to 96% of patients with primary biliary cirrhosis. AMA are also occasionally found in sera of patients with other liver diseases, including chronic active hepatitis, cryptogenic cirrhosis, as well as in patients with clinical but no biochemical evidence of liver disease. The M2 antigen used is strongly associated with PBC, while other types (M1, M2, M5, and M6) are associated with a wide variety of conditions. |
| CPT Code(s) | 86381 |
| Service Provided By |  |
| Lab Section | Reference Lab |