MYD88 L265P Mutation Detection PCR Quant
Order Name
MYD88 L265P PCR
Test Number: 6906225
Revision Date 12/06/2024
Test Number: 6906225
Revision Date 12/06/2024
| Test Name | Methodology | LOINC Code |
|---|---|---|
|
MYD88 L265P Mutation Detection PCR Quant
|
Polymerase Chain Reaction/Real Time |
| SPECIMEN REQUIREMENTS | ||||
|---|---|---|---|---|
| Specimen | Specimen Volume (min) | Specimen Type | Specimen Container | Transport Environment |
| Preferred | 5 mL (1 mL) | Whole Blood | EDTA (Lavender Top) | Room Temperature |
| Alternate 1 | 3 mL (1 mL) | Bone Marrow | Heparin No Gel Tube | Room Temperature |
| Alternate 2 | 1 | Tissue | Paraffin Block | Room Temperature |
| Alternate 3 | 1 | Fresh Tissue | Sterile Screwtop Container | Room Temperature |
| Alternate 4 | 2-10 | Tissue | Glass Slides with Holder | Room Temperature |
| Instructions | Specimen Requirements: Blood, bone marrow, fresh tissue, paraffin-embedded tissue Container: EDTA lavender top tube, heparin (green top) tube, sterile container Collection: For Paraphin Embedded Tissue, 2 10-slides Storage Instructions: If a specimen is unsuitable or is suspected of being contaminated by another specimen, the specimen is rejected. Unsuitable specimens include, but are not limited to: sample >48 hours old; frozen whole blood, serum or marrow; a leaking tube; clotted blood or marrow; a grossly hemolyzed specimen or otherwise visibly degraded or unsuitable; and specimens containing suspicious foreign material. |
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| GENERAL INFORMATION | |
|---|---|
| Testing Schedule | Varies |
| Expected TAT | 5-10 days |
| Clinical Use | Use: Detection of MYD88 L265P mutation helps differentiate lymphoplasmacytic lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM) from other lymphomas. |
| CPT Code(s) | 81305 |
| Internal Comments | 12/29/18: Updated CPT (SN) 2/15/35: Updated notes and instructions (SN) 10/30/23: Updated per Julie Kurlin hlp tkt instructions section, hdm 12/03/2024 - move back to LCA 12/6/2024 removed from ARUP version - bm Useful in distinguishing lymphoplasmacytic lymphoma (LPL) from other low-grade B-cell lymphoproliferative disorders which may be in the differential diagnosis. Monitoring of individuals with LPL diagnosis and previously identified MYD88 L265P mutation |
| Service Provided By |  |
| Lab Section | Reference Lab |