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St. John Health System
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MYD88 L265P Mutation Detection PCR Quant

Order Name MYD88 L265P PCR
Test Number: 6906225
Revision Date 10/30/2023
Test Name Methodology LOINC Code
MYD88 L265P Mutation Detection PCR Quant
Polymerase Chain Reaction/Real Time  
SPECIMEN REQUIREMENTS
Specimen Specimen Volume (min) Specimen Type Specimen Container Transport Environment
Preferred 5 mL (1 mL) Whole Blood EDTA (Lavender Top) Refrigerated
Instructions Specimen Type/Preparation:
   Whole Blood: Do not freeze. Transport 5 mL whole blood. (Min: 1 mL)
   Bone Marrow: Do not freeze. Transport 3 mL bone marrow. (Min: 1 mL)
   FFPE Tumor Tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat.
Storage/Transport Temperature:
   Whole Blood, Bone Marrow: Refrigerated.
   FFPE Tumor Tissue: Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Unacceptable Conditions:
   Whole Blood, Bone Marrow : Plasma, Serum. Specimens collected in anticoagulants other than EDTA or sodium heparin. Clotted or grossly hemolyzed specimens.
   FFPE Tumor Tissue: Specimens fixed/processed in alternative fixatives, heavy metal fixatives (B-4 or B-5), or tissue sections on slides. Decalcified specimens.
Stability:
   
Whole Blood or Bone Marrow:  Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable.
   FFPE Tumor Tissue:  Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable.
GENERAL INFORMATION
Testing Schedule Varies  
Expected TAT 5-10 days  
Clinical Use Useful in distinguishing lymphoplasmacytic lymphoma (LPL) from other low-grade B-cell lymphoproliferative disorders which may be in the differential diagnosis.
Monitoring of individuals with LPL diagnosis and previously identified MYD88 L265P mutation 
Notes Reference Lab: ARUP
Test Code: 2009318
Click Here to view information on the ARUP website.
CPT Code(s) 81305
Service Provided By Labcorp Oklahoma, Inc.
Lab Section Reference Lab